应用热分析法鉴别根茎类药材及其提取物

Application of DSC method in identification of root or rhizome herbs and their extracts

目的:应用差示扫描量热法(DSC)分别对不同产地的丹参、甘草和赤芍的粉末、醇提物和水提物进行分析鉴别。方法:以参比物为α-Al2O3,在静态空气气氛条件下,固定DSC量程、升温速率和温度范围,根据图谱峰形和特征进行比较鉴别。结果:丹参、甘草、赤芍的原药材粉末、醇提物和水提物吸热峰和放热峰位置略有不同,但来自两种产地的DSC图谱峰形基本一致。结论:实验初步表明DSC法具有试量微样化、不用溶剂、曲线易于解析、快速简便等优点,可作为根、根茎类药材及其提取物的鉴别方法之一。

AIM： To apply Differential Scanning Calorimetry （DSC） identifying powder aqueous extracts and alcohol extracts of Radix et Rhizoma Salviae miltiorrhizae, Radix et Rhizoma Glycyrrhizae and Radix Paeonia rubra. METHODS： α-Al2O3 was taken as the reference substance and under static state air condition, with the determination of the measuring range ,the heating rate and temperature range of each herb or its extracts, the herbs were identified by comparing the characteristics and the peak profiles of their chromatography. RESULTS： There were the tiny differences in DSC chromatography among powder, aqueous extracts and alcohol extracts, DSC chromatography of the same herbs from two different areas were very close to each other. CONCLUSION： With great advantages of DSC method, such as very small amount of drugs, solvent-free. It is easy, quick and convenient to apply chromatography analyses.