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铁负荷与人体健康 被引量:11

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摘要 铁负荷指身体内的铁含量增加,伴有或不伴有器官的损害。遗传因素、后天获得性因素、膳食因素等可促使机体发生铁负荷。机体铁负荷会引起肝脏疾病、糖尿病、心脑血管疾病等多种疾病的发生。铁负荷带来的机体损害日益受到人们的重视。本文综述了铁负荷的发生、铁负荷与慢性病的研究进展及铁负荷的治疗。
作者 韩巍 王朝旭
出处 《国外医学(卫生学分册)》 2008年第1期52-56,共5页 Foreign Medical Sciences(Section of Hygiene)
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  • 1FRAZER D M, WILKINS S J, BECKER E M, et al. A rapid decrease in the expression of DMTI and Dcytb but not Iregl or hephaestin explains the mucosal block phenomenon of iron absorption [ J ]. Gut, 2003,52 : 340- 346.
  • 2LATUNDE-DADA G O, SIMPSON R J, MCKIE A T. Recent advances in mammalian haem transport[J]. Trends Biochem Sci, 2006,31(3) : 182-188.
  • 3GANZ T. Cellular iron: ferroportin is the only way out [J]. Cell Metab, 2005,1(3) :155-157.
  • 4WEST A P, BENNETT M J, SELLERS V M, et al. Comparison of the interaction of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE [J]. J Biol Chem, 2000, 275:38135-38138.
  • 5OATES P S, THOMAS C, FREITAS E, et al. Gene expression of divalent metal transporter 1 and transferrin receptor in duodenum of Belgrade rats[ J]. Am J Physiol Gastrointest Liver Physiol, 2000,278 : G930-936.
  • 6GANZ T, NEMETH E. Iron imports.Ⅳ. Hepcidin and regulation of body iron metabolism [ J ]. Am J Physiol Gastrointest Liver Physiol, 2006,290(2) : G199-203.
  • 7LE GAC G, FeREC C. The molecular genetics of haemochromatosis[ J]. Eur J Hum Genet, 2005, 13( 11 ) : 1172-1185.
  • 8KEW M C, ASARE G A. Dietary iron overload in the African and hepatocellular carcinoma [ J ]. Liver Int, 2007,27(6) :735-741.
  • 9KANG J O. Chronic iron overload and toxicity[J]. Clin Lab Sci, 2001, 14(3) :209-219.
  • 10CORRADINI E, FERRARA F, PIETRANGELO A. Iron and the liver[ J ] . Pediatr Endocrinol Rev, 2004,2 ( Suppl 2) : 245-248.

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