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细胞色素P4503A5基因多态性的研究进展 被引量:9

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出处 《中国药房》 CAS CSCD 北大核心 2008年第4期304-307,共4页 China Pharmacy
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参考文献20

  • 1Kuehl P, Zhang J, Lin Y, et al . Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression[J ] .Nat Genet, 2001,27(4) : 383.
  • 2Hu YF,He J ,Chen GL, et al. CYP3A5* 3 and CYP3A4 *18 single nucleotide polymorphisms in a Chinese population [J ] . Clin Chim Acta , 2005,353( 1- 2) : 187.
  • 3王汉平,毛平,谢健晋,许艳丽,莫文健,杜庆华,朱志刚.细胞色素P-450 3A5基因类型影响造血干细胞移植患者血环孢素浓度[J].中华器官移植杂志,2005,26(4):207-209. 被引量:5
  • 4Haufroid V, Mourad M, van Kerckhove V, et al . The effect of CYP3A5 and MDRI(ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels instable renal transplant patients [ J ] . Pharmacogenetics , 2004,14 ( 3 ): 147.
  • 5Hesselink DA, van Schaik RH, van der Heiden IP,et al . Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR 1 genes and pharmacokinetics of the calcineur in inhibitors cyclosporine and tacrolimus[J ]. Clin Pharmacol Ther, 2003,74(3) : 245.
  • 6张鑫,刘志红,郑敬民,陈朝红,唐政,陈劲松,黎磊石.细胞色素P450 3A5和多药耐药基因1基因多态性在肾移植患者他克莫司血药浓度监测中的应用[J].肾脏病与透析肾移植杂志,2004,13(4):313-317. 被引量:21
  • 7Le Meur Y,Djebli N,Szelag JC,et al .CYP3A5* 3 influences sirolimus oral clearance in de novo and stable renal transplant recipients[J]. Clin Pharmacol Ther , 2006,80(1) : 51.
  • 8Kivisto KT, Niemi M, Schaeffeler E, et al. Lipid - lowering response to statins is affected by CYP3A5 polymorphism[J ]. Pharmacogenetics, 2004 , 14(8) : 523.
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  • 10Kim KA, Park PW, Lee OJ, et al .Effect of polymorphic CYP3A5 genotype on the single - dose simvastatin pharmacokinetics in healthy subjects[J] .J Clin Pharmacol, 2007,47(1) :87.

二级参考文献31

  • 1Paulussen A, Lavrijsen K, Bohets H, et al. Two linked mutations in tran scriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of polymorphic activity in humans. Pharmacogenetics,2000,10(5) :415
  • 2Lee SJ, Usmani K, Chanas B, et al. Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups. Pharmacogenetics, 2003,13: 461
  • 3Thiebaut F, Tsuruo T, Hamada H, et al. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.Proc Natl Acad Sci U S A, 1987,84:7735
  • 4Hebert MF. Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. Adv Drug Deliv Rev, 1997,27(2-3) :201
  • 5Zhang Y, Benet LZ. The gut as a barrier to drug absorption: Combined role of cytochrome P450 3A and P-glycoprotein. Clin Pharmacokinet,2001,40:159
  • 6Spencer CM, Goa KL, Gillis JC. Tacrolimus. An update of its pharmacology and clinical efficacy in the management of organ transplantation.Drugs, 1997,54:925
  • 7Zheng H, Webber S, Zeevi A, et al. Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms.Am J Transplant, 2003,3 (4): 477
  • 8Hesselink DA, van Schaik RH, van der Heiden IP, et al. Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyelosporine and tacrolimus. Clin Pharmacol Ther,2003,74(3) :245
  • 9Thervet E, Anglicheau D, King B, et al. Impact of cytochrome p450 3A5genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients. Transplantation,2003,76(8) :1233
  • 10Zheng H, Zeevi A, Schuetz E, et al. Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism.J Clin Pharmacol, 2004,44(2): 135

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