缺血性卒中病机假说——“气虚生风”临床依据研究

Systematic study of the pathogenesis hypothesis in ischemic stroke——clinical basis for the pathogenesis hypothesis of "Qi deficiency generating wind"

目的:为构建缺血性卒中"气虚生风"病机假说提供临床依据。方法:搜集益气方药治疗缺血性卒中急性期的临床研究文献,筛选合格研究,应用Jadad评分标准进行质量评价,运用Meta-分析等方法统计相关数据。结果:黄芪注射液、刺五加注射液治疗缺血性卒中急性期安全有效,且统计分析结果稳定。结论:气虚证可发生于缺血性卒中急性期,气虚是其病机变化之一,据此提出缺血性卒中"气虚生风"的病机假说。

Objective： to provide a clinical basis for the pathogenesis hypothesis of “Qi deficiency generating wind” in ischemic stroke. Methods： by means of collecting clinical research literatures on replenishing Qi prescriptions for the treatment of ischemic stroke in the acute phase, screening qualified research, evaluating the quality according to Jadad standards and analyzing the statistical data with Meta-analysis. Results： Huangqi injection and Ciwujia injection are safe and effective for the treatment of ischemic stroke in the acute phase and the statistical analytical results are stable. Conclusion： Qi deficiency syndrome, as one of its pathological changes, can be detected in the acute phase of ischemie stroke,on the basis of which the pathogenesis hypothesis of “Qi deficiency generating wind” in ischemic stroke is thus presented.