术前心痛定治疗高血压对胸部硬膜外麻醉的血液动力学影响

HAEMODYNMIC CHANGES DURING THORACIC EPIDURAL ANAESTHESIA IN HYPERTENSIVE PATIENTS TREATED PREOPERATIVELY WITH NIFEDIPINE

为观察心痛定与胸部硬膜外麻醉时上胸段交感神经阻滞，对血液动力学有无协同抑制作用，用无创心功能监测心痛定治疗组（NTG）与未治疗组（UTG）各50例高血压患者，上胸段硬膜外麻醉时血液动力学改变。结果显示：二者共同作用使高止压患者动脉压下降，心脏后负荷减轻，心肌氧耗下降，心室射血功能改善，心脏指数明显增加，无1例发生循环衰竭。表明心痛定用于上胸段硬膜外麻醉前治疗高血压，是有效而安全的。

In order to observe whether there are cooperating negative effects on haemodynamics between Nifedipine (NIF) and thoracic sympathetic blocks following Thoracic Epidural Anesthesia (TEA ), the haemodynamic effects of thoracic epidural anesthesia were investigated on hyperten-sive patients, 50 cases in NIF treated group (NIG)and 50 cases in untreated group (UTG), with non-invasive cardiovascular monitoring techniques- Theresult showed that the cooperating effects of NIFand TEA might decrease MAP, SVR and RPP, in-crease CI, but there was no one case of circulative failure. Our observation results indicate that NIF may be efficiently and safely used for treating hyper-tension before the TEA.