摘要
目的:筛选茵陈发挥保肝作用的有效部位。方法:用系统溶剂分离法将茵陈分离成极性不同的组分。采用四氯化碳(CCl4)致小鼠急性肝损伤模型,按赖氏法测定小鼠血清中AST,ALT的活性。结果:茵陈的三氯甲烷提取物能明显降低CCl4引起的AST,ALT增高。结论:茵陈三氯甲烷提取部位为其发挥保肝作用的有效部位。
Objective： To screen the effective fraction with liver protection activity from Artemisia scoparia Waldst. et Kit. Methods： Fractions of Artemisia scoparia Waldst, et Kit. with different polarities were obtained from a serious of extraction solutions, The activities of AST and ALT were measured in liver injury mouse model induced by carbon tetrachloride （CCl4）. Results： In this experiment, chloroform extract of Artemisia scoparia Waldst. et Kit. can significantly decrease the serum transaminase （ALT, AST） activities in liver injury mouse model induced by carbon tetrachloride. Conclusion： The chloroform extract is the effective part of Artemisia scoparia Waldst. et Kit, for liver protection.
出处
《现代生物医学进展》
CAS
2008年第1期114-115,共2页
Progress in Modern Biomedicine
关键词
茵陈
保肝作用
活性部位
Artemisia scoparia Waldst.et Kit.
Liver protection
Active fraction
