磁敏感加权成像在颅内肿瘤成像的初步应用

The initial clinical application of susceptibility weighted imaging in intracranialtumor

目的：初步分析磁共振磁敏感加权成像（susceptibility weighted imaging，SWI）在颅内肿瘤显像的应用价值。方法：自2006年5月～9月共21例颅内占位，男9例，女12例，平均年龄52岁。应用西门子3．0TMR扫描仪（Trio Tim），头部表面线圈，扫描序列包括常规序列和SWI序列，其中常规序列包括FLASH序列T1WI、TSE序列T2WI和FLAIR序列，扫描包括横断位和矢状位。全部病例均在静脉注射Gd-DTPA后，进行轴位和矢状位增强扫描，对比剂剂量为0．1mmol／kg体重。将SWI图像与常规序列比较，并与CT和病理对照分析。结果：21例颅内肿瘤中脑膜瘤7例、胶质母细胞6例、弥漫性星形细胞瘤2例，间变性少突胶质细胞瘤2例，转移瘤2例、生殖细胞瘤1例，大脑胶质瘤病1例。与CT及病理对照，SWI较常规序列可以更好地显示肿瘤，确定边界、显示瘤内出血、血管结构及钙化，显示瘤周水肿及静脉受压情况。结论：SWI可以作为颅内肿瘤显像的重要补充序列，结合其他序列对肿瘤提供更全面、精确的信息。

Objective： To apply susceptibility weighted imaging （SWI） in intracranial masses and to evaluate its diagnostic value. Methods：SWI was applied to 21 patients （12 females and 9 males, 15 - 74 years old, mean age 52 years） with intracranial masses at 3.0T. The SWI images were compared with conventional sequences including T1, post-contrast T1, T2 and fluid- attenuated inversion recovery （FLAIR）, CT and pathology were obtained.Results：The pathologic results of the patients were meningioma in 6 cases, ghoblastoma in 6 cases, diffuse astrocytoma in 2 cases, anaplastic oligodendroghal in 2 cases, metastatic tumor in 2 cases, germimoma in 1 case, ghomatesis cerbfi in 1 case. Compared with CT and pathology, SWI was superior to conventional sequence in tumor visibility, boundary definition. Identifying blood products, venous vasculature, calcification in tumor, edema and vein around tumor was better in SWI. Conclusion： SWI can be used as a complementary sequence for tumor imaging, which offers more complete and detailed information combining with other sequence.