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妊娠期高血压对脐血脂联素水平影响及其与胰岛素的关系

Measurements of the adiponectin levels in the cord blood with pregnancy-induced hypertension(PIH)and the relationship between adiponectin and insulin level
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摘要 目的探讨妊娠期高血压(妊高征,PIH)对胎儿脐血脂联素水平的影响及脂联素与胰岛素之间的关系。方法妊高征母亲所生新生儿60例,分为3组:妊娠期高血压组(PIH 1)23例、子间疒前期轻度组(PIH 2)22例、子间疒前期重度组(PIH 3)15例,正常对照组40例,采用放射免疫分析法(RIA)测定脐血脂联素、胰岛素水平,并分析两者相关性。结果①PIH组脐血脂联素水平低于正常对照组,且随母亲PIH程度的加重呈进行性的下降,组间比较差异有统计学意义(P<0.05);②PIH组脐血胰岛素水平低于正常对照组,且随母亲PIH程度的加重呈进行性的下降,组间比较差异无统计学意义(P>0.05);③PIH组脐血脂联素水平与胰岛素水平呈正相关(r=0.293,P<0.05)。结论妊高征时宫内不利环境影响胎儿内分泌代谢的调节,且随母亲妊高征程度的加重而加重。
出处 《临床儿科杂志》 CAS CSCD 北大核心 2008年第1期45-48,共4页 Journal of Clinical Pediatrics
关键词 妊娠高血压 脐血 脂联素 胰岛素 pregnancy-induced hypertension cord blood adiponectin insulin
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