稀释性自身输血在择期手术中的类试验研究

Quasi-Experiment Study on Hemodilution Auto-Transfusion for Selective Operation

目的探讨稀释性自身输血在择期手术中的可行性和安全性。方法选取2003-2006年菏泽市立医院46例稀释性自身输血患者为实验组,随机抽取50例异体输血患者为对照组,观察病人血气分析指标和血液指标,数据用SPSS 11.0软件对数据进行t检验和配对t检验。结果稀释性自身输血和异体输血病人术前血红蛋白水平差异无统计学意义(P>0.05);输血30 min后与麻醉前PH、PaO2、PaCO2、SB、BE的变化水平均无明显差异(P>0.05);术后第1天与术前HCT、HGB、PLT、PT的变化水平均无明显差异(P>0.05)。结论稀释性自体输血是一项安全、简便、有效的临床治疗手段,可以应用于择期手术。

Objective To explore the feasibility and security of the hemodilution auto-transfusion for selective operation. Methods 46 cases who received hemodilution auto-transfusion for selective operation from 2003 to 2006 year in Heze municipal hospital were selected as experimental group, and another 50 cases that received variant transfusion were selected as control group. Then the patients＇ blood gas analysis index and blood index were observed and analyzed by SPSS11.0 usingt-test method and pair t-test method. Results There was no difference at the HGB level between the two groups （P〉0.05）. In addition, the charge of patients＇PH, PaO2, PaCO2, SB, and BE between pre-anesthetize and 30 minutes of post transfusion showed no difference （P 〉 0.05）. Furthermore, the charge of patients＇ HCT, HGB, PLT, and PT between preoperative and the first day of postoperative showed no difference （P〉0.05）. Conclusion The hemodilution auto-transfusion is a safe, convenient and effective clinical therapeutic tool, which can be applied for selective operation.