深圳市2起人感染猪链球菌病疫情的流行病学调查

Epidemiological Investigation on Two Cases of Human Streptococcus suis Infection in Shenzhen

目的查明我市2起人感染猪链球菌病的感染途径和流行特征,为制定预防控制措施提供依据。方法开展流行病学调查,采集脑脊液标本,用血平板进行细菌培养、分离,用PCR鉴定。结果患者手部有外伤且有生猪肉接触史,临床上潜伏期短,病程进展迅速,均为脑膜炎型。患者脑脊液中分离的细菌经生化和PCR检测结果为猪链球菌Ⅱ型。病人经过及时抢救均脱离了危险。结论2起疫情为散发疫情,相互间无流行病学联系。传播途径为接触被猪链球菌污染的生猪肉经破损皮肤而传染。应加强卫生知识宣传和教育,提高肉食品加工人员的自我保护能力,同时要提高医务人员的诊治水平。

Objective （ 1 ） To determine the etiology, mode of transmission, and epidemiological characteristics of human Streptococcus suis infection and （2） to-develop strategy of control and prevention in the future, Methods Epidemiological studies and descriptive analysis were performed. Blood agar culture and PCR were used for the detection of Streptococcus suis in cerebrospinal fluids （CSF）. Results Those infected patients with meningitis had a history of contacting raw meat with open wound fingers. The incubation was short and the disease progression such as the development of hemorrhagic spots or patches on their skins, and streptococcal toxic shock-like syndrome was fast. The strains isolated from CSF were identified as Streptococcus suis type Ⅱ by both biochemical tests and PCR. The patients were all recovered. Conclusion Two sporadic cases of Streptococcus suis infection were reported in Shenzhen. The mode of transmission was mainly due to contact of open wounded skin with contaminated swine meat. Health education should be provided to the breeders and slaughters. Training should also be given to the medical professionals about Streptococcus suis infection.