甲状旁腺机能低下和肾功能衰竭晚期并发弥漫性结膜钙质沉着征(英文)

Diffuse conjunctival calcinosis in hyperparathyroidism and end stage renal failure

目的:报告1例甲状旁腺机能低下和肾功能衰竭晚期并发弥漫性结膜钙质沉着征患者。方法:病例报告。结果:患者,男,35岁,因为双眼异物感,伴发红、流泪1mo就诊。患者患有甲状旁腺机能低下征和肾功能衰竭晚期,既往做过甲状旁腺次全切除术。查:双眼视力1. 0,结膜弥漫性沉着物和充血,结膜组织病理学检查报告,结膜基质层下有较多钙质沉着,血清钙明显高于正常,血清磷正常。通过局部用类固醇激素(倍他米松)和肌肉降钙素后,患者眼部症状明显减轻。结论:弥漫性症状性结膜钙质沉着是一种罕见的眼部钙质沉着征,甲状旁腺机能低下和肾功能衰竭是引发的因素。

AIM： To describe a case of diffuse conjunctival calcinosis in hyperpararthyroidism and end stage renal failure patient. METHODS： A case report. RESULTS： A 35-year-old gentleman, known case of hyperparathyroidism with subtotal parathyroidectomy done and end stage renal failure, presented with one month history of foreign body sensation of both eyes associated with redness and tearing. On examination, vision was 6/6 OU with diffuse conjunctival.deposits and congestion. Conjunctival histopathological examination showed multiple foci of calcium deposits in the subepithelial stroma. Serum calcium was markedly raised and serum phosphorus was normal. His eye symptoms was reduced with topical steroid （betamethasone） and intramuscular calcitonin. CONCLUSION： Diffuse and symptomatic conjunctival calcinosis is uncommon condition of ocular calcium deposition. Hyperparathyroidism and renal failure are the contributing factors for the development of it.