细胞形态相似的血液病鉴别诊断分析

Differential diagnosis of the cell plesiomorphism between hematologic diseases

目的鉴别分析两组疾病包括反应性浆细胞比例增高、多发性骨髓瘤(MM)与原发性巨球蛋白血症,慢性粒细胞白血病(CML)与感染细胞形态学的特征。方法分别对各组病例进行回顾分析血象,骨髓象及特殊染色的特征。结果MM、原发性巨球蛋白血症及浆细胞比例增高骨髓象的浆细胞形态有显著性差异(P<0.05);CML与感染两组在嗜酸、嗜碱粒细胞总数、粒细胞形态异常、红系,巨核系抑制及中性粒细胞碱性磷酸酶NAP染色等方面均有显著性差异(P<0.005)。结论严格掌握几类疾病细胞形态学的不同点有助于对疑难疾病的正确诊断。

Objective To differentiate and diagnose cell plesiomorphism betweet： two groups including reactive high plasmocyte and multiple nryelonta（MM） and primary macroglobulinaemia; chronic myelocytic leukemia（CML） and infection. Methods retrospective analyze the characters of hemogram,bone marrow and specific stain in each group. Results there are significant deviation（ P 〈 0.05 ） between reactive high plasmocyte,MM and primary macroglobulinaemia in plasmocte shape;there are significant deviatiou （ P 〈 0.005） between CML and infection in eosino.basophilic cell.paramorphia of granular cell,restrained erythrocyte and megakaryocyte and NAP. Conclusion It is essential to master morphocytology for the final diagnosis of difficult diseases.