期刊文献+

磷酸肌酸钠对慢性心衰患者心功能的影响 被引量:12

下载PDF
导出
摘要 目的:观察磷酸肌酸钠(CP)对慢性心衰患者心功能的影响。方法:慢性心衰患者78例随机分为常规治疗(对照组)39例和磷酸肌酸钠治疗(治疗组)39例。对照组给予地高辛片、利尿剂、ACEI、ARB或β受体阻滞剂治疗;治疗组在此基础上加用磷酸肌酸钠(唯嘉能)1.0g,静脉滴注,1天2次,连用10-14天。观察治疗前及治疗后1个月患者的心功能。结果:与治疗前相比,治疗组左室收缩末内径(LVESD)、左室收缩末容量(LVESV)、左室射血分数(EF)明显改善。治疗组临床显效率、总有效率,左室舒张末内径、LVESD、LVESV、LVEF与对照组比较,差异均有显著性意义。结论:CP可辅助治疗慢性心衰,改善心功能,特别是左室收缩功能。
出处 《浙江中西医结合杂志》 2008年第1期15-16,共2页 Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献3

二级参考文献23

  • 1唐继志,李忠杰,方永生,孙华群.充血性心力衰竭患者自主神经功能与心功能等相关因素的研究[J].中国全科医学,2004,7(14):1041-1043. 被引量:9
  • 2Robinson LA,Braimbridge MV,Hearse DJ. Enhanced myocardial protection with high-energy phosphates in St.Thomas hospital cardioplegic solution: synergism of adenosine triphosphate and creatine phosphate. J Thorac Cardiovasc Surg, 1987, 93(3): 415-427.
  • 3Hellgren L,Kvidal P,Stahle E. Improve early results after heart valve surgery over the last decade. Eur J Cardiothorac Surg, 2002,22(6): 904-911.
  • 4Moibenko AA,Markeenko GI,Kotsurba VN,et al. Effects of exogenous phosphocreatine on endothelium and endothelium dependent vascular reactions in immune cardiac injury. Curr Ther Res,1992,52(8): 791-801.
  • 5Kata AM.Metabolism of the failing heart[J].Cardioscience,1993,4:199-203.
  • 6Conway MA,Allis J,Ouewrkerk R,et al.Detection of phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 32 magnetic resonance spectoscopy[J].Lancet,1992,338:973-978.
  • 7Hardy CJ,Weiss RG,Bottomley PA,et al.Altered myocardial high energy phosphatemetabolites in patients with dilated cardiomyopathy[J].AM Heart J,1991,122:795-801.
  • 8Neubauer S,Hern M,Pabsr T,et al.Contribution of 31 p-magnetic resonance spectroscopy to understanding of dilatod heart muscle disease[J].Eur Heart J,1995,16:115-118.
  • 9Saks VA,Strumia E.Phosphocreatine mocular and cellular aspets of the mechanism of cardioprotective action[J].Curr Ther Res,1992,53:585-598.
  • 10Sergio F,Linzia C,Fibrazio P,et al.Hemodynamic effects of phosphato in patients with congestive heart failure.A double-blind comparison trial versus placebo[J].Clin Cardiol,l996,l9:699-703.

共引文献69

同被引文献81

引证文献12

二级引证文献57

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部