摘要
目的:探讨经皮椎体成形术(PVP)治疗椎体肿瘤性病变的临床效果。方法:应用PVP治疗32例44个椎体良恶性肿瘤病变。在C型臂X光机透视导向下经皮穿刺到病变椎体后注入骨水泥。记录患者术前、术后24h、术后1周、术后1个月的疼痛视觉模拟划线得分(VAS),观察止痛效果和并发症。结果:44个椎体皆一次穿刺成功,穿刺成功率100%。一月后疼痛缓解程度为:完全缓解(CR)者8例,部分缓解(PR)者21例,轻度缓解(MR)者2例,无效(NR)者1例,总有效率(CR+PR)为90.6%(29/32)。患者术前与术后24h、术后1周、术后1个月的VAS得分差异有显著性意义(P<0.05)。PVP术后8个椎体发生无症状的骨水泥渗漏无1例椎体塌陷加重或发生新的骨折,无1例发生严重并发症。结论:PVP治疗椎体肿瘤性病变成功率高,效果良好。
Objective：To investigate the clinical efficacy of percutaneous vertebroplasty （PVP） in the treatment of vertebral tumour. Methods：Of 32 cases with 44 vertebral tumors including metastatic tumor （26 patients,36 vertebral bodies involved）, myeloma （2 patients, 4 vertebral bodies）, hemangioma （4 patients, 4 vertebral bodies）, percutaneous puncture of vertebral lesions were performed under C-arm fluoroscopy and bone cement was injected. The visual analogue scale point （VAS） （10 point scale） were recorded before and 24 hours,one week and one month after vertebroplasty respectively. Result of pain relief and complications were observed. Results： 100% success rate of PVP was obtained. Complete relief （CR） was assessed in 21 patients,partial relief （PR） in 21 patients,mild relief （MR） in 2 patients and no pain relief in 1 patient 30 days after operation. The total rate of pain relief （CR＋PR） was 90.6% （29 /32 patients）. There are significant differences among the scores of VAS with different time points （before operation;24h,1w,1m after operation） （P〈0. 05）. After PVP,apart from asymptomatic bone cement leakage around 8 vertebral bodies,no new vertebral fracture as well as aggravation of vertebral body compression was revealed in all patients during the follow-up of 1-12 monthes. No major complications occurred. Conclusion： The clinical effect of percutaneous vertebroplasty for vertebral tumour is safe and satisfactory.
出处
《放射学实践》
2008年第1期69-72,共4页
Radiologic Practice
基金
江苏省“135”工程重点人才基金(RC2003097)
