多普勒超声心动图对经胸放疗期间左室舒张功能的评价

Evaluation of left ventricular diastolic function during thoracic radiation treatment by Doppler echocardiography

目的:应用多普勒超声心动图监测经胸放疗期间左室舒张功能的变化。方法:36例经胸放射治疗的患者,进行两次多普勒超声心动图检查,首诊检查:放射治疗前1～3天;复诊检查:放射治疗结束当天。测量舒张期二尖瓣口血流频谱及二尖瓣环运动频谱的两峰比值(E/A,e/a)。结果:舒张期二尖瓣口血流频谱及二尖瓣环运动频谱的两峰值比率均显示,两次测量结果间存在显著性差异(E/A:0.77±0.19 vs 0.69±0.13,e/a:0.82±0.31 vs 0.75±0.19,均P<0.05)。结论:经胸放疗期间左室舒张功能受损,多普勒超声心动图可及时作出诊断。

Objective： To investigate the variation of left ventricular diastolic function during thoracic radiation treatment using Doppler ecbocardiography. Methods： The study group consisted of 36 patients with thoracic radiotherapy. The patients were examined twice, the first examination： 1-3 days before the radiation treatment; the second examination： the day of radia- tion treatment was finished. Doppler ecbocardiographic examinations were performed by measuring the ratio of two peaks of mitral inflow Doppler velocity and mitral annular diastolic velocity profile（E/A, e/a）. Results： E/A and e/a between two examinations were significantly different （E/A： 0.77±0.19 vs 0.69±0.13, c/a： 0.82±0.31 vs 0.75±0.19, both P〈0.05）. Conclusion＇. Left ventricular diastolic function was damaged during thoracic radiation treatment, which can be diagnosed by Doppler ecbocardiography in time.