白地霉的化学成分研究

Chemical Constituents from Geotrichum candidum

白地霉(Geotrichum candidumLink)固体发酵培养物,经乙醇提取、柱层析分离得到了7个化合物。通过光谱分析,分别鉴定为亮氨酸(1)、尿嘧啶(2)、胸腺嘧啶(3)、焦儿茶酸(4)、4-羟基苯甲酸(5)、3,5-二羟基苯甲酸(6)和7,8-dimethylalloxazine(7)。7个化合物均是首次从白地霉中得到。

Seven compounds were isolated from the cultures of Geotrichum candidum Link. On the basis of their spectral data, they were identified as leucine （1）, uracil （2）, thymine （3）, pyrocatechuic acid （4）, p-hydroxybenzoic acid （5）, 3, 5-dihydroxybenzoic acid （6）, and 7, 8-dimethylalloxazine （7）. All compounds are isolated from this fungus for the first time.