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子宫珠蛋白与子宫内膜癌

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摘要 子宫珠蛋白(UG)是类固醇激素诱导分泌的、进化上高度保守的多功能蛋白。UG具有肿瘤抑制、抗炎及免疫调节等多种生物学活性,人的UG基因定位在染色体11q12.3-13.1,此区域是在许多癌症中被经常重排和删除的区域。本文就UG的结构、分布、生物学功能及其在正常子宫内膜和子宫内膜癌中的表达等方面的进展进行综述。
作者 刘岩丽 刘萍
出处 《中国优生与遗传杂志》 2008年第2期122-123,126,共3页 Chinese Journal of Birth Health & Heredity
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