超声及肝功能指标对婴儿肝炎综合征的意义

Evaluating Infantile Hepatitis Syndrome by Color Doppler Ultrasonography and Routine Liver Function

目的探讨彩色多普勒超声(Color Doppler ultrasonography,CDUS)结合常规肝功能指标对婴儿肝炎综合征(infant hepatitis syndrome,IHS)的临床应用价值。方法彩色多普勒超声检测30例IHS患儿肝脏大小、回声、肝中及肝右静脉(HV)血流频谱波形,同时进行常规肝功能项目的检测,包括总胆红素(TB)、直接胆红素(DB)、丙氨酸氨基转移酶(ALT),按临床病程分组,并以门诊健康体检儿为对照组。结果随着病情的好转,ALT、TB及DB各指标逐渐减低,分别为(30.23±12.36)IU/L、(24.64±16.51)μmol/L、(17.54±12.62)μmol/L,甚至部分降至正常,肝静脉血流频谱波形由连续平坦波形及波幅减低但无反向血流的异常波形型逐渐向正常波发展。结论彩色多普勒超声结合常规肝功能指标对婴儿肝炎综合征病情转归具有重要临床意义。

Objective To evaluate the practical value of Color Doppler ultrasonography（CDUS）and routine liver function in the patients with infant hepatitis syndrome（IHS）.Methods Thirty cases of IHS were examined by Color Doppler ultrasonography,including the size,echo of liver,the waveform of the middle and right hepatic veins.Meantime,all cases with IHS were checked up routine liver function,which were classified into groups based upon disease course,and Compared with clinic health infants.Results Accompanying the disease recovery,all of ALT,TB and DB decreased respectively（30.23±12.36）IU/L,（24.64±16.51）μmol/L,（17.54±12.62）μmol/L and parts of them even decreased to normal level,at the same time the waveform of the hepatic veins also from anomaly waveform such as lasting low breadth to normal waveform.Conclusion CDUS and routine liver function may play an important role in disease conversion in the patients with IHS.