无创双水平气道正压通气治疗超高龄急性肺水肿的临床观察

Clinical Observation on Efficacy of Non-invasive Bi-level Positive Airway Pressure in Treatment of Superelderly Patients With Acute Pulmonary Edema

目的:观察无创双水平气道正压通气治疗超高龄老年人急性肺水肿的临床疗效及安全性。方法:将70例80岁以上超高龄老年人急性肺水肿患者分为治疗组和对照组,治疗组在药物抢救治疗的同时,采用BiPAP呼吸机进行无创通气治疗;对照组以相同药物抢救治疗的同时,辅以常规鼻导管吸氧治疗。观察两组治疗前后氧饱和度(SaO2)、呼吸频率(R)、静息心率(RHR)及临床症状缓解所需时间。结果:治疗组SaO2回升快,临床症状缓解迅速,两组比较有显著性差异(P<0.01)。结论:BiPAP无创正压通气治疗超高龄老年人急性肺水肿患者能迅速纠正缺氧及改善心肺功能、提高抢救成功率,缩短病程。

Objective.. To observe the clinical efficacy and safety of non-invasive bi-level positive pressure （BiPAP） ventilation in treatment of superelderly patients with acute pulmonary edema （APE）. Methods： Seventy patients aged over 80 years old with APE were divided into 2 groups： treatment group and control group. Patients in treatment group were treated by non-invasive BiPAP as well as concomitant conventional drug therapy; control group received the same drug therapy as well as oxygen inhalation via nasal tube. Blood oxygen saturation（SaO2 ）, respiration rate, resting heart rate （RHR） and the time required for relieving of clinical symptoms were observed in both groups. Results： SaO2 raised more quickly and clinical symptoms relieved more rapidly in treatment group than those in control group （P〈0. 01）. Conclusion： Non-invasive BiPAP ventilation is an effective and safe metheod in superelderly patients with APE. Non-invasive BiPAP ventilation can correct hypoxia quickly, improve cardiopulmonary function, increase the successful rate of salvage and shorten the duration of hospitalization.