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重组人红细胞生成素对大鼠心肌细胞凋亡的影响

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摘要 心肌梗死后心肌细胞供血不足,产生缺氧损伤,伴随着血管再通,心梗局部再灌,又产生超氧损伤。我们在体外条件下,通过模拟心梗局部的环境变化,探讨重组人红细胞生成素(rHu-EPO)对心肌细胞的缺氧和超氧损伤是否具有保护作用。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2007年第12期1598-1598,共1页 Chinese Journal of Experimental Surgery
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参考文献5

  • 1Siren AL, Fratelli M, Brines M, et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc Natl Acad Sci USA,2001,98: 4044-4049.
  • 2Zweier JL, Flaherty JT, Weisfeldt ML. Direct measurement of free radical generation following reperfusion of isehemic myocardium. Proc Natl Aead Sei USA, 1987, 84 : 1404-1407.
  • 3杜心灵,叶亮,夏家红.重组人红细胞生成素对大鼠心肌梗死的治疗作用[J].中华实验外科杂志,2004,21(11):1315-1316. 被引量:7
  • 4Brines ML, Ghezzi P, Keenan S, et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci USA, 2000,97 : 10526-10531.
  • 5袁彪,赵忠,赵胜,张杨杨.大鼠心脏移植后心肌细胞凋亡的研究[J].中华实验外科杂志,2007,24(2):209-210. 被引量:3

二级参考文献8

  • 1Calvillo L,Latini R,Kajstura J,et al.Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling.Proc Natl Acad Sci USA,2003,100:4802-4806.
  • 2Palojoki E,Saraste A,Eriksson A,et al.Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats.Am J Physiol Heart Circ Physiol,2001,280:2726-2731.
  • 3Ono K,Lindesy ES.Improved technique of heart transplantation in rats.J Thorac Cardiovasc Surg,1969,57:225-229.
  • 4Ritter T,Schroder G,Risch K,et al.Ischemia/reperfusion injurymediated down-regulation of adhenoxirus-mediated gene expression in a rat heart transplantation model is inhibited by co-application of a TNFRp55-Ig chimeric construct.Gene Ther,2000,7:1238.
  • 5Billigham ME,Cary NRB,Hamond EH,et al.A working formulation for the heart rejection study group.J Heart Transplant,1990,9:587-593.
  • 6Susin SA,Lorenzo HK,Zamzami N,et al.Molecular characterization of mitochondrial apoptosis-inducing factor.Nature,1999,397:441-446.
  • 7Kromer C,Reed JC.Mitochondrial control of cell death.Nature Med,2000,6:513-519.
  • 8Thomas CT,Guanggen C,Kiyohiro O,et al.Balance expression of mitochiondirial apoptosis regulatory proteins correlates with long-term survival of cardiac allografts.Am J Physiol Heart Circ Physiol,2003,285:2832-2841.

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