精神分裂症住院病人用药性别差异情况调查分析

To investigate the gender difference in antipsychotic drug used among schizophrenic inpatients

目的:为了解男女精神分裂症患者住院用药情况。方法:对我院精神科封闭病房住院接受抗精神病药物治疗的233例精神分裂症患者不同性别用药进行回顾性分析,其中男性117例,女姓116例。结果:男、女患者精神药物使用频率居首的为氯氮平,居前五位的均为氯氮平,舒必利,利培酮,氯丙嗪,奋乃静;单一抗精神病药物为主;非典型抗精神病药物的使用率超过典型抗精神病药物;服用前五位抗精神病药物的日平均最大剂量女性高;精神药物联合治疗男性高于女性。结论:住院精神分裂症病人在抗精神病药联合治疗上及部分药物的日平均最大剂量有性别差异。

Objective： To investigate the gender difference in antipsychotic drug used among schizophrenic inpatients. Method： 233 inpatients who suffer from schizophrenia （male 117,Female 116） were sampled, and the clinical data of these patients were compared retrospectively. Result The rate of clozapine used was the highest among all psychotropic drugs, and the drugs frequently used were clozapine, sulpride, risperidone, chlorpromazine and perphanzine. Most inpatients were treated with single drug. The rate of atypical psychotropics used was higher than that of typical psychotropics. The mean maximum daily dose of the first five psychotropics was higher in female patients than that in male. The rate of using psychotropic drug combining treatment is higher in male patients than that in female. Conclusion The using of psychotropic drugs combiming treatment and mean maximum daily dose of some parts psychotropics depend on the difference of gender among schizophrenic inpatients.