摘要
预先镇痛或超前镇痛(preemptive analgesia)临床和动物试验研究的结果存在着明显差异,其原因可能与对手术疼痛病理生理过程以及预先镇痛概念的认识不全面、镇痛研究方案设计不规范和评价体系不完善有关。近年来提出的预防性镇痛(preventive analgesia)新概念提倡将镇痛治疗时间拓展到术前、术中和术后,采用持续、多模式镇痛方式覆盖整个围手术期,以彻底消除手术应激创伤引起的疼痛,并防止和抑制中枢及外周的敏化,从而取得完全、长时间的有效镇痛。
As to now, the results of clinical investigations and animal researches on preemptive analgesia are variable. The reason of this situation lies in uncomprehensive understanding of pathophysiologic process of surgery and true concept of preemptive analgesia, and/or unformalized design and evaluation system for analgesia researches. The concept of preventive analgesia emerged in recent years emphasizes extending the analgesia from preoperation to intraoperation and postoperation, and advocates totally abolishing pain induced by surgical stress and peripheral and/or central sensitization with continuous and muhimodel analgesia, and finally fulfills completely and long term ideal analgesia.
出处
《实用疼痛学杂志》
2007年第6期401-404,共4页
Pain Clinic Journal
