摘要
Andrographis paniculata Nees 广泛地对发烧，痢疾，腹泻，发炎，和酸的喉咙为传统的药和帮助被使用了。在这研究， andrographolide，这植物的主要部件从 A 的叶子被提取。用超级批评二氧化碳的 paniculata。操作压力从 7.50 被改变到 20MPa，温度从 30 ° C 被改变到 60 ° C，并且流动率从 0.5 被改变到 4ml · m in-1。最好的抽取条件为 A 的一件 3g 样品发生在 10MPa， 40 ° C，和 2ml · m in-1 的流动率。paniculata 弄干地面的叶子。测量抽取率被发现每工作时间每在叶子在场的 andrographolide 的克关于 andrographolide 的 0.0174g。未来研究必须集中于在象超级批评二氧化碳的温度，压力，和流动率那样的各种各样的操作参数之间的相互作用。
Andrographis paniculata Nees has been extensively used for traditional medicine and help against fever dysentery, diarrhoea, inflammation, and sore throat. In this study, andrographolide, the main component of this plant was extracted from the leaves of A. paniculata using supercritical carbon dioxide. The operating pressures were varied from 7.50 to 20MPa, the temperatures were varied from 30℃ to 60℃, and the flow rates were varied from 0.5 to 4ml.min^-1. The best extraction condition occurred at 10MPa, 40℃, and a flow rate of 2ml.min^-1 for a 3g sample of A. paniculata ground-dried leaves. The measured extraction rate was found to be about 0.0174g of andrographolide per gram of andrographolide present in the leaves per hour of operation. The future studies must focus on the interaction between the various operating parameters such as temperature, pressure, and flow rate of supercritical carbon dioxide.
基金
Supported by the Intensification of Research in Priority Areas Project (IRPA)
Ministry of Science, Technology and Innovation,Malaysia (No.09-02-03-0101-EA0001).
