前列腺消融术加卡介苗膀胱灌注治疗慢性非细菌性前列腺炎的疗效观察

Study of Effect of BCG Bladder Irrigation after Prostatic Ablation for Chronic Nonbacterial Prostatitis

目的探讨前列腺消融术后卡介苗膀胱灌注治疗慢性非细菌性前列腺炎的疗效。方法将100例慢性非细菌性前列腺患者随机分成两组,A组50例,采用经尿道前列腺消融术、卡介苗混合灌注液灌注膀胱;B组50例,除灌注液内不含卡介苗外,余治疗方案与A组相同。结果组内比较两组治疗后前列腺液的WBC计数、IL-8、TNF-α含量及NIH-CPSI评分均较治疗前显著降低,且治疗后A组在NIH-CPSI评分、IL-8、TNF-α含量上均低于B组(P<0.05或P<0.01)。结论前列腺消融术后加用卡介苗膀胱灌注治疗慢性非细菌性前列腺炎疗效优于常规灌注。

Objective To investigate the therapeutic effect of prostatic ablation followed by BCG bladder irrigation for chronic nonbacterial prostatitis. Methods 100 cases of chronic nonbacterial prostatitis patients were divided into 2 groups randomly. 50 cases in group A received bladder irrigation by BCG and regular drugs after prostatic ablation. 50 cases in group B received the same methods except the BCG bladder irrigation. Results The WBC account, IL-8 and TNF-α levels, and NIH-CPSI score were significantly decreased after treatment in both groups. And in group A, the IL-8 and TNF-α levels and NIH-CPSI score were significantly decreased after treatment comparing with those of group B. Conclusion It provides a more promotional effect of BCG bladder irrigation after prostatic ablation for chronic nonbacterial prostatitis.