抑癌基因ING家族研究进展

Advances in Research on Tumor Suppressor Genes ING Fimily

ING家族是近些年才被发现一个侯选肿瘤抑制基因家族,因其家族成员广泛参与基因转录的调控、细胞增殖、凋亡、细胞衰老、接触抑制、DNA损伤修补及抑制血管形成等,和肿瘤的发生发展密切相关而受到关注。

ING（inhibitor of growth）family has emerged as strong candidate tumor suppressor genes in recent years,which its members fimctions in regulation of genes transcription,cell profiferation,apoptosis,contact inhibition,DNA repair and angiogenesis. ING family is followed with interest due to its role on tumorigenesis and progression.