急性心肌梗死患者心电学和心脏形态学指标的变化

The Changes of Heart Electrophysiology Index and Heart Morphology Signs in Patients with AMI

目的:观察QT变异度(QTV)等因素和急性心肌梗死患者恶性室性心律失常(MVA)的相关性。方法:50例急性心肌梗死(AMI)患者和50例健康人分别作为AMI组和对照组,根据入选者心电学指标及心脏形态学指标,分别进行AMI组和对照组以及AMI组组内比较。结果:(1)心肌梗死患者的QT间期变异度和QT间期变异系数(QTVC)明显低于对照组;(2)心率变异性(HRV)和QTV,QTVC,左室舒张末内径(LVd),左室射血分数(LVEF)与MVA存在相关性。结论:QTV,QTVC在心肌梗死后与MVA存在相关性,和传统预测值LVd、LVEF同样有效,可能成为独立的预测AMI后MVA和猝死的指标。

Objective：To observe the relationship of QT interval variability（QTV） and the index signs of the malignant ventricular arrhythmia（MVA） in the patients with the acute myocardial infarction（AMI）.Methods：50 patients diagnosed exactly as AMI in hospital and 50 health persons were collected as AMI group and control group,respectively.To compare three kinds of information such as heart electrophysiology index signs,heart morphology signs,ect,were compared between AMI patients and health persons also among the AMI patients themselves.Results：（1）The QTV（21.64±6.07）ms vs（31.58±8.44）ms,（P〈0.01）,QTCV（5.22±2.04）% vs（7.91±2.21）%（P〈0.01） of the AMI patients were significantly lower than those of the control group.（2）The occurrence frequency and serious degrees of the MVA were related with HRV,LVd,LVEF,QTV,QTCV.Conclusion：The QTV,QTCV are related with MVA of AMI patients and their diagnose value are not less than those classical signs such as HRV,LVd,LVEF,etc.So QTV,QTCV may be the new and independent index sign to MVA and sudden cordial death（SCD） of AMI patients.