摘要
丙烯酸酯是一类具有良好生物活性的化合物,由于它作用机制新颖、环境友好,故其分子设计和合成及生物活性成为目前农药创制的热点之一,按其在农药应用方面的不同活性作用进行分类,综述了丙烯酸酯及其类似物的合成、生物活性与除草活性方面构效关系的研究进展.
Cyanoacrylates and their analogues are an important class of compounds with high bioactivities. Recently, studies on the molecular designing, synthesizing and bioactivities of α-cyanoacrylates have attracted more and more attentions according to their characteristics of novel mechanism and friendly-environment. Recent advances in the synthesis, structure, biological activity and structure-activity relationships (SAR) of 2-cyanoacrylate and its analogues are reviewed emphatically on their applying on pesticide based on different bioactivities.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2008年第1期17-28,共12页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.20672024)
国家973重点基础研究发展计划(No.2003CB114404)
国家“十一·五”科技支撑计划(No.2006BAE01A02-5)资助项目
关键词
丙烯酸酯
合成
生物活性
构效关系
acrylate
synthesis
bioactivity
structure-activity relationships