α-氰基丙烯酸酯及其衍生物的合成与农药生物活性研究进展

Recent Advances in the Synthesis and Biological Activity on Pesticide ofα-Cyanoacrylates and Its Analognes

丙烯酸酯是一类具有良好生物活性的化合物,由于它作用机制新颖、环境友好,故其分子设计和合成及生物活性成为目前农药创制的热点之一,按其在农药应用方面的不同活性作用进行分类,综述了丙烯酸酯及其类似物的合成、生物活性与除草活性方面构效关系的研究进展.

Cyanoacrylates and their analogues are an important class of compounds with high bioactivities. Recently, studies on the molecular designing, synthesizing and bioactivities of α-cyanoacrylates have attracted more and more attentions according to their characteristics of novel mechanism and friendly-environment. Recent advances in the synthesis, structure, biological activity and structure-activity relationships （SAR） of 2-cyanoacrylate and its analogues are reviewed emphatically on their applying on pesticide based on different bioactivities.