老年人与中青年人胃癌临床特征比较分析

Comparative Analysis of the Clinical Characteristics of the Gastric Cancer in the Old and Young and Middle-aged Patients

目的探讨老年与中青年胃癌不同的临床特征。方法回顾性分析2003年7月至2004年12月行胃癌切除手术老年组(≥60岁)61例及中青年组(<60岁)48例患者的临床资料。结果老年组胃癌患者吞咽困难的出现率明显高于中青年组(P<0.05);老年组胃癌患者贲门胃底的发病率明显高于中青年组(P<0.01);老年组中分化腺癌发生率明显高于中青年组(P<0.05);两组胃癌手术方式比较无明显差异性。结论老年组胃癌与中青年组的临床特征有所不同,中青年组胃癌的病理分化程度较差,预后相对不良。

Objective To study the different clinical characteristics between the old and young and middle-aged patients with gastric carcinoma. Methods From July 2003 to December 2004,61 old patients and 48 young and middle-aged patients with gastric carcinoma were treated with surgical treatment, The clinical characteristics of the patients were analysed retrospectively. Results The dysphagia rate of the old patients was significantly higher than that of the young and middle-aged group （P 〈 0. 05）, Gastric carcinoma of the cardia and fundus in the old patients was more common than that in the young and middle-aged group（ P 〈 0.01 ）. More patients in the old group had well-differentiated adenocarcinoma than that in the young and middle-aged group（ P 〈 0. 05 ）, There was no difference of operative methods between these two groups. Conclusion There are different clinicopathological characteristics between the old and young and middle-aged patients with gastric carcinoma. Poorly differentiatiated carcinoma is more common in the young and middle-aged patients with gastric carcinoma, and the prognosis in this group of patients is more unfavorable.