线粒体体外代谢热动力学模型及其演化优化研究

Studies on the Thermokinetic Model of Mitochondrial Metabolism and its Evolutionary Optimization

导出了线粒体体外代谢的热动力学方程（MTD）；探讨了它和指数模型的关系将演化计算技术引入生物热化学领域，用MTD方程和演化计算技术，对文献报导的八种鱼肝线粒体体外代谢的热动力学参数进行了全局优化．

Thether mokinetic equation(MTD)of tochondrialmetabolism was educed and there lation between this equation and exponential model was ex amined.The technology of evo-lutionary computation was firstintr oducedto there sear chofbiological thermochemistry.The thermokineticp arameters of some mitochondrial external metabolism were globally optidrized with the evolution arycomputation program about MTD,which was programmed yourselves,and excellent result was obtained.