进展性脑卒中的多因素分析

Analysis of multiple factors in progressive stroke

目的探讨高血压、糖尿病、颈动脉硬化斑块与进展性脑卒中的相互关系。方法回顾性分析48例进展性卒中患者临床资料,对其血压、血糖、血脂及病变的严重程度进行相关分析。结果48例进展性脑卒中伴高血压者43例,其中35例收缩压<150mmHg(20kPa),舒张压>90mmHg(12kPa),脉压>30mmHg(4kPa),明显高于对照组(P<0.01);合并糖尿病者30例,明显高于对照组15例(P<0.01)。颈动脉超声检查发现颈动脉硬化斑块者43例,其中软斑21例,溃疡斑21例,硬斑1例。结论高血压、糖尿病及动脉硬化斑块与进展性脑卒中的发生发展密切相关,这些危险因素的研究对防治进展性脑卒中有重要临床意义。

Objective To explore the relationships among hypertension diabetes, carotid artery arteriosclerotic plaques and progressive stroke（PS）. Methods Forty-eight cases PS patients were retrospectively studied, blood pressure,blood glucose and blood lipid level as well as carotid artery arteriosclerotic plaques in PS were analyzed. Results Forty-three cases were accompanied with hypertension. Among them ,43 patients＇ systolic pressure was less than 20 kPa and diastolic pressure more than 12 kPa,which were much higher than those of control group（P〈0. 01）. In addition, 30 patients were accompanied with diabetes and the number was obviously higher than that of the control group which had only 15 cases （P〈0.01）. At the same time, soft plaque of 21 cases, ulcer plaque of 21 cases and hard plaque of 1 case were found in 43 cases. The rate was higher than that of control group （P〈0.01）. Conclusion Hypertension,diabetes and arteriosclerotic plaques are closely related to PS. To study these risk factors is very important to preventing PS.