期刊文献+

依达拉奉对急性脑梗死患者神经元特异性烯醇化酶变化的影响 被引量:8

下载PDF
导出
摘要 目的观察依达拉奉对急性脑梗死患者的神经元特异性烯醇化酶(NSE)变化的影响及评价其对脑梗死的治疗效果。方法选择76例急性脑梗死患者在治疗前、治疗第3d和治疗1周后血清NSE变化和神经功能缺损评分变化。结果急性脑梗死常规治疗组和依达拉奉治疗组治疗前血清NSE均高于正常对照组(P<0.01),依达拉奉治疗第3d时,患者血清NSE浓度明显下降,低于常规治疗组。神经功能缺损评分低于常规治疗组(P<0.05)。结论依达拉奉有保护脑神经元作用,并能有效改善急性脑梗死的神经功能缺损。
作者 黄菊明
出处 《中国实用神经疾病杂志》 2008年第2期73-75,共3页 Chinese Journal of Practical Nervous Diseases
  • 相关文献

参考文献4

二级参考文献23

  • 1Carhuapoma JR, Wang PY, Beauchamp NJ, et a1. Diffusion weighted MRI and proton MR spectroscopic imaging in the study of secondary neuronal injury after intracerebral hemorrhage. Stroke, 2000,31(3): 726-732.
  • 2Michael N, Louis D, Admas RE, et al.Cerebral blood flow is symmetricaly reduced in patients with intracerebral hemorrhage. Neurology, 1998, 50: A338.
  • 3Xue M, Del-Bigio MR. Intracortical hemorrhage injury in rats: relationship between blood fractions and brain cell death. Stroke, 2000,31(7): 1721-1727.
  • 4Peeling J, Yan HJ, Corbett D, et al. Effect of FK-506 on inflammation and behavioral outcome following intracerebral hemorrhage in rat. Exp Neurol, 2001, 167(2): 341-347.
  • 5Heiss WD, Kracht LW, Thicl A, et al. Penumbral probability thresholds of cortical flumazenil binding and bbod flow predicting tissue outcome in patients with cerebral ischaemia. Brain, 2001, 124: 20-29.
  • 6Mendebw AD. Mechanisms of ischemic brain damage with intracerebral hemorrhage. Stroke, 1993, 24:115-119.
  • 7Yang GY, Betz AL, Chenevert TL, et al. Experimental intracerebral hemorrhage: relationship between brain edema, blood flow, and blood-brain barrier permeability in rats. J Neurosurg, 1994, 81 (1):93-102.
  • 8Nath FP, Kelly PT, Jenkins A, et al. Effects of experimental intracerebral hemorrhage on blood flow, capillary permeability, and histochemistry. J Neurosurg, 1987, 66(4)555-562.
  • 9Matz PG, Weinstein PR, Sharp FR. Hemne oxygenase-1 and heat shock protein 70 induction in glia and neurons throughout rat brain after experimental intracerebral hemorrhage. Neurosurgery, 1997, 40(1): 152-160.
  • 10Tanizaki Y. Improvement of cerebral blood flow following stereotactic surgery in patients with putaminal haemorrhage. Acta Neurochir (Wien), 1988, 90(3-4):103-110.

共引文献42977

同被引文献156

引证文献8

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部