促渗剂对定喘膏透皮渗透的影响

Effect of Azone on Skin Penetration Effect of Asthma Plaster

应用改进的Ｆｒａｎｚ扩散小池进行体外透皮吸收试验，采用薄层扫描法测定定喘膏中活性成分延胡索乙素的含量，研究不同浓度的氮酮对定喘膏透皮吸收的影响。结果表明该定喘膏中氮酮浓度为２％～３％时，延胡索乙素累积透皮扩散量最高。

An in vitro skin penetration and absorption test was made using thin layer scanning method to determine the active component tetrahydropalmatine in the Asthma Plaster to find out the effect of different concentrations of azone on the skin penetration and absorption of the Asthma Plaster.The result showed that when the concentration was 2%～3%,best skin penetration and absorption was achieved.Neither higher nor lower concentrations are desirable.