1Klautke G, Feyerherd P, Ludwig K, et al. Ntensified concurrent chemoradio-therapy with 5-fluorouracil and ifinotecan as neoadjuvant treatment in pat/ents with locally advanced rectal cancer [ J]. Br J Cancer,2005,92 (7) : 1215 - 1220.
2Chau I, Brown G, Cunningham D,et al. Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer [ J ]. J Clin Oncol,2006,24 (4) :668 - 674.
3Hotheinz RD, Hofisberger K, Woemle C, et al. Phase I trial of cetuximab in combination with capecitabine, weekly ifinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer[J]. Int J Radiat Oncol Biol Phys,2006,66 (5) :1384 -1390.
4Crane CH, Skibber JM, Bimbaum JH, et al. The addition of continuous infusion 5-FU to preoperative radiationtherapy increased tumor response, leading to increased sphincter preservation in locally- advanced rectal cancer[J]. Int J Radiat Oncol Biol Phys, 2003,57( 1 ) :84 - 89.
5Ryan R, Gibbons D, Hyland JM, et al. Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer[ J ]. Histopathology,2005,47 (2) : 141 - 146.
6Lam CW,Chen WT,Liu MT,et al. Effect of preoperative concurrent chemoradiotherapy in locally advanced low rectal cancer after . radical resection surgery[J]. Int Surg,2005,90( 1 ) :53 -59.
7Osti MF,Valeriani M, Masoni L, et al. Neoadjuvant chemoradiation for locally advanced carcinoma of the rectum[ J]. Turnoff, 2004,90(3) :303 -309.
8Mantello G, Berardi R, Cardinali M, et al. Feasibility of preoperative chemoradiation in rectal cancer patients aged 70 and older [J]. J Exp Clin Cancer Res,2005,24(4) :541 -546.
9Rodriguez-Ramirez SE, Uribe A, Ruiz-Garcia EB, et al. Risk factors for anastomotic leakage after preoperative chemoradiafion therapy and low anterior resection with total mesorectal excision for locally advanced rectal cancer[ J ] ] Rev Invest Clin,2006,58 (3) :204 -210.
10Wiehmann MW, Meyer G, Adam M, et al. Detrimental irnmuno-logic effects of preoperative ehemoradiotherapy in advanced rectal cancer[J]. Dis Colon Rectum,2003,46(7) :875 -887.
