Implanta的药理作用及临床观察

Pharmacological and clinical observation on Implanta

为观察韩美药品公司(Hanmi Pharm.Co.Ltd)生产的环孢素A软胶囊(Implanta)的药理作用及临床效果,对30例肾移植患者应用Implanta。30例患者分为A、B两组,A组12例为刚行肾移植手术者,B组18例为肾移植后半年至4年者,原来服用山地明或赛斯平。结果表明,在血药浓度、抑制排斥的效果、移植肾功能的恢复及不良反应等方面,与山地明和赛斯平一样。临床结果表明Implanta是安全有效的。

In order to observe the pharmacological action and clinical effects of Implanta (from Hanmi Pharm. Co. Ltd) on renal transplantation, 30 patients receiving renal transplantation were treated with Implanta. Among the 30 patients, 12 patients (group A) just underwent renal transplantation, the remaining 18 cases underwent the operation 0.5 to 4 years ago and administered Sundimin or Cyspin. The results showed that the blood concentration, the effcets of inhibiting the rejection, the function recovery of transplanted kidney and side effects of Implanta were the same as those of Sundimin or Cyspin. It was conlcuded that Implanta was safe and effective.