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环孢菌素D简介 被引量:2

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摘要 环孢菌素是由不完全真菌的多孔木霉和柱盘孢菌属培养、发酵后产生的代谢产物.其主要产物环孢茵素A(CsA)具有很强的免疫抑制作用.CsA能抑制T细胞的繁殖作用,从而改变T细胞的免疫反应;也作用于B细胞亚群.因此,临床上除了用于肝、肾等的器官移植,防止器官的排斥反应外,还可用于治疗自身免疫性疾病,如类风湿、牛皮癣、眼葡萄膜炎、I型糖尿病、慢性活动性Crohn’s回肠炎、多发性硬化症等等.
作者 刘文 黄威
出处 《国外医药(抗生素分册)》 CAS 1997年第4期286-291,共6页 World Notes on Antibiotics
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同被引文献33

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