体外受精-胚胎移植妇女焦虑和抑郁及相关因素

Anxiety,depression and correlates of women with in vitro fertilization and embryo transfer

目的了解安徽省某生殖中心体外受精-胚胎移植（in vitro fertilization and embryo transfer，IVF-ET）妇女的焦虑、抑郁症状及相关因素，为进行干预研究提供依据。方法对安徽省225名IVF—ET妇女，应用焦虑自评量表（SAS）、流调中心用抑郁量表（CES-D）及应付方式问卷、婚姻调适测定表进行匿名问卷调查。结果焦虑症状检出率为15．6％，抑郁症状检出率为32．0％；随着应付方式中自责因子分升高抑郁症状的危险性显著增加，解决问题、求助因子分升高抑郁症状的可能性降低；婚龄在8年～、居住在农村抑郁症状的危险性增加；不孕症持续时间为6年～、治疗持续时间3年～、不孕症既往治疗费2万元～、不孕原因由女方、夫妇双方因素引起与妇女焦虑症状相关联。结论IVF-ET妇女焦虑、抑郁症状普遍，应针对其危险因素进行干预研究，提高IVF—ET妇女心理健康水平。

Objeetive To know the prevalence of anxiety and depression and it＇s risk factors among infertile women with the treatment of in vitro fertilization and embryo transfer（ IVF - ET）, documented for anxiety and depression intervention. Methods A total of 225 infertile women with IVF-ET were investigated with SAS, CES-D , coping style questionnaire and marriage accommodating questionnaire. Results The prevalence of anxiety and depression were 15.6 % and 32.0 % respectively. With the scores of self-accusation increased, the risk of depression increosed. With the scores of problem-solving, help-seeking increased, the risk of depression decreased. Marrital years more than 8 years and resident in rural were associated with depression. Infertility time more than 6 years, receiving treatment time at least 3 years, treatment cost over 20 thousands yuan, infertility cause due to women and couples were associated with anxiety. Conelusion Anxiety and depression syndromes are common among infertile women with IVF-ET. Preventive intervention design should be aimed at related factors of anxiety and depression.