汉族和维吾尔族居民血尿酸及高尿酸血症分析

Analysis of uric acid level and prevalence of hyperuricmia in Han and Uygur ethnic population

目的了解新疆乌鲁木齐市汉族和维吾尔族健康体检人群高尿酸血症发病水平。方法采用现况研究方法，调查乌鲁木齐市20～80岁汉族和维吾尔族健康体检者5560名，采用尿酸酶法检测血尿酸水平，比较不同人群高尿酸血症检出率。结果汉族人群血尿酸值平均为（344．23±103．22）μmol／L，其中男性、女性分别为（393．08±86．97），（259．83±68．89）μmol／L；维吾尔族人群平均为（310．23±106．85）μmol／L，其中男性、女性分别为（364．09±99．52），（246．42±75．44）μmol／L。汉族高于维族，男性高于女性，差异均有统计学意义（P〈0．05）。高尿酸血症检出率汉族人群27．3％（男性37．7％，女性9．5％），维吾尔族人群为17．58％（男性27．4％，女性5．7％）。汉族男女性平均患病年龄分别为38．26和42．94岁，维吾尔族男女性平均患病年龄分别为46．42和51．83岁。结论乌鲁木齐市汉族人群血尿酸值和高尿酸血症患病检出率均高于维吾尔族，也高于国内其他地区调查结果；汉族男女的发病年龄均低于维吾尔族。

Objective To know the uric acid level in Han and Uygur ethnic and the prevalence of hyperuricemia of two ethicities in Xinjiang. Methods From January to December 2005, the blood samples were collected for serum uric acid（SUA） detection among the population including 5560 subjects aged 20 to 80 years. Results The mean of SUA in Han ethnicity was 344.23 ± 103.22μmol/L（393.08 ± 86.97μmol/L for men and 259.83 ± 69.89μmol/L for women）, and in Uygur ethnic was 310.68 ± 106.85 μmol/L（364.09 ± 99.52 μmol/L in men and 246.42 ± 75.44 μmol/L in women）. Han ethnic was higher than Uygur ethnic and man was higher than woman（ P 〈 0.05） in two ethnicities. The prevalence of hyperuricemia in Han ethnic was 27.3% （37.7% in men and 9.5% in women） and Uygur ethnic was 17.5% （27.4% in man and 5.7% in women）. The average age of hyperuricmia occured for Han was 38.26 year in men and 42.94 year in women, and for Uygur ethnic was 46.42 year in men and 51.33 year in women. Conclusion The uric acid level and the prevalence of hyperuricmia of Han were higher than Uygur ethnic population in Urumchi, and were higher than other place in China.