农村高血压人群良性前列腺增生影响因素分析

Analysis of risk factors of benign prostatic hyperplasia in hypertensive population in rural community

目的探讨农村地区高血压人群中，良性前列腺增生（BPH）的患病情况及其影响因素。方法采用人群为基础的流行病学调查。收集安徽省安庆农村地区50岁以上男性高血压患者621例，其中患有良性前列腺增生（BPH）患者300例，非良性前列腺增生患者321例。采用Logistic逐步回归分析高血压患者伴发良性前列腺增生的影响因素。单因素分析采用t检验、x^2检验，多因素分析采用Logistic逐步回归。结果Logistic逐步回归结果显示，高血压人群中BPH患病与以下5种因素有关：年龄（OR=1．077，95％CI=1．046～1．109）、30岁性生活频次（OR=1．027，95％CI=1．004～1．051）、食盐摄入量（OR=2．007，95％CI=1．324～3．043）、水果摄入量（OR=0．628，95％CI=0．431～0．914）以及心理紧张度（OR=2．128，95％CI=1．439～3．146）。结论高水果摄入可能是高血压人群中BPH的保护因素；年龄、30岁性生活过频、食盐摄入过高以及心理紧张可能是BPH的危险因素。

Objective To investigate the prevalence of benign prostatic hyperplasia （BPH） in hypertensive populations and the risk factors for BPH in rural community, Methods A population - based epidemiological investigation was conducted to collect 621 hypertensive male patients over 50 years old who are local residents in Anqing, Anhui, In this population, 300 subjects coincided with BPH and another 321 subjects did not, Logistic regression was used for analysis of risk factors of BPH. T test, x^2 test, and stepwise Logistic regression were used for univariate analysis and multivariate analysis, respectively, Results Logistic regression analysis showed that BPH was related to five major risk factors： age（ OR = 1. 077, 9596 CI： 1. 046- 1.109）, sexual intercourse frequence in 30 years old （ OR = 1. 027, 95% CI ; 1.004 - 1. 051 ）, monthly salt intake （ OR = 2,007,95% CI： 1.324- 3.043）, weekly fruits intake（ OR = 0.628, 95% CI： 0.431 -- 0.914）, mental tensity （OR = 2.128, 95% CI ： 1.439--3.146）. Conclusion Age, high sexual intercourse frequence in 30 years old, high salt intake, mental tensity were possible risk factors for BPH, while heavy fruits intake was possible protective factor.