摘要
目的生物反应器是组织工程的重要载体,旋转式生物反应器是目前研究的热点。本文探讨了可提供优良环境条件的可控生物反应器系统的设计与实践。方法系统采用PWM可调驱动直流电机等;同时可对温度等物理量进行检测,并反馈控制调节反应器;测控系统与PC连接,可实现远程视频监测控等,使整个组织生物反应器系统初步实现了分步式、自动化。结果经实验系统培养所得到的细胞相对于一般培养细胞其生物学特性有相当的改善。结论自动化旋转式生物反应器驱动控制的实践具有较大的应用推广价值。
Objective Horizontal rotating bioreactor is a kind of advanced bioreactor, which is the basic and important facility in tissue engineering. In this paper,we developed a controlable horizontal rotating bioreactor system, which can supple choiceness environment condition for cells cultur, e. Methods System used PWM modulation to drive DC-motor, used sensor to detect and control the temperature of bioreactor reactor, and the system connected with PC to remote watch test and control. The system primarily achieved distributed control, Results The biology characteristic of the cells that were cultivated by this system improved greatly. Conclusion This practices of realization controlable horizontal rotating bioreactor system have bigger value in applications.
出处
《航天医学与医学工程》
CAS
CSCD
北大核心
2008年第1期61-65,共5页
Space Medicine & Medical Engineering
基金
四川大学创新基金资助(2005CF14)
四川大学应用基础研究(07JY029-071)
