睡眠呼吸障碍与代谢综合征——二位一体的心血管危险因素？

Sleep breath disorder and metabolic syndrome ——the duplex of risk factor of cardiovascular diseases？

睡眠呼吸障碍（SBD）和代谢综合征（MS）都是重要的心血管危险因素，流行病学研究发现二者存在高度发病相关性，而且都呈全球性的流行态势，均导致不良的心血管结局，对人类健康具有广泛而深远的影响。因此，其相互关系和作用如何？各自在心血管病发生发展过程中起着怎样的作用？是目前正在深入探讨的重要临床问题。本文着重阐述有关SBD与MS发病相关性及其病理生理机制方面的研究进展，并提出二者可能为二位一体的心血管危险因素的假说。

Sleep breath disorder（SBD） and metabolic syndrome（MS） are both important risk factors of cardiovascular diseases,which are pandemic globally with highly epidemiological correlation of each other and corresponding with adverse cardiovascular outcome, so affect the health of human beings deeply and widespread. The increasingly important clinical problems such as what about their correlation and role of each other, how about the pathophysiological process which take part in the cardiovascular diseases respectively,are respected interestingly nowadays. This paper focuses on the updates about investigations of the pathogenetic correlation and pathophysiological mechanism of SBD and MS,and a novel hypothesis has been arisen that SBD and MS may be the duplex of risk factors of cardiovascular diseases.