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糖尿病肾病患者D-二聚体与尿微量清蛋白检测的临床价值 被引量:4

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摘要 目的探讨血浆D-二聚体(D-D)在糖尿病肾病(DN)患者中的变化及应用价值。方法根据尿微量清蛋白排泄率(UAER)将92例2型糖尿病患者分为单纯糖尿病组(SDM组)、早期糖尿病肾病组(EDN组)和临床糖尿病肾病组(CDN组),另选30例健康体检者作为对照组,分别测定各组血浆D-D的水平。结果D-D水平在糖尿病各组与对照组之间比较差异有统计学意义(P<0.05),EDN组和CDN组显著高于SDM组(P<0.05),CDN组显著高于EDN组。D-D与UAER呈显著正相关(r=0.376,P<0.05)。结论DN患者血浆D-D水平随着UAER的增加而升高,二者之间关系密切,对D-D水平的检测可能对2型糖尿病肾病的早期发现和病情判断有着重要临床价值。
出处 《检验医学与临床》 CAS 2008年第3期152-153,共2页 Laboratory Medicine and Clinic
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