老年真菌性肺炎的菌群分布与临床危险因素调查

Nosocomial Pneumonia Caused by Fungi in Hospitalized Senile Patients:A Clinical Investigation

目的探讨老年真菌性肺炎的菌种分布和危险因素,制定有效的治疗方案与预防措施。方法以《医院感染诊断标准》为依据,查阅2001年1月-2005年12月医院老年患者的病历,对135例老年真菌性肺炎病例的有关资料进行统计分析。结果135例肺炎患者真菌感染中,白色假丝酵母菌占第1位,为54.8%;热带假丝酵母菌占第2位,为20.0%,老年患者罹患真菌性肺炎的临床危险因素为原发基础疾病、侵入性诊疗操作、激素与抗菌药物的广泛应用等。结论采取支持疗法,治疗原发疾病、减少侵入性诊疗、合理使用抗菌药物等综合措施,预防与控制老年真菌性肺炎的发病率。

OBJECTIVE To investigate clinical status,distribution of the genera,and risk factors of pneumonia caused by fungi in hospitalized senile patients.METHODS The notices of hospitalized senile patients from Jan 2000 to Apr 2003 were analyzed according to Diagnosis Standard of Nosocomial Infection published by National Ministry of Health.RESULTS Totally 135 cases were collected.The isolating ratio of Candida albicans ranked first（54.8%）,followed by C.tropicalis（20.0%）.The risk factors included underlying diseases,invasive surgical procedure,and prolonged hormones and antibiotics therapy.CONCLUSIONS To prevent and control pneumonia caused by fungi in hospitalized senile patients,the measures such as curing the underlying diseases,reducing invasive surgical procedures,and using antibiotics reasonably should be adopted.