摘要
在离体大鼠膈神经－膈肌标本（膈ＮＭＰ）上观察了常用的肟类重活化剂氯磷定、碘磷定、双复磷和ＨＩ－６对抗氧化乐果对标本的抑制作用，发现４种药物在对抗氧化乐果抑制离体大鼠膈ＮＭＰ的作用中均有对中毒酶的重活化作用，其强弱排序为：双复磷＞氯磷定、碘磷定＞ＨＩ－６。
The antagonistic effects of the common oximes PAM Cl, PAM I, obidoxime and HI 6 on inhibition of the isolated rat phrenic neuromuscular transmission by omethoate were observed and it was found that all the four kinds of oximes could reactivate ChE inhibited by omethoate in rat phrenic nerve diaphragm preparation in vitro. The order of the reactivation potency was : obidoxime>PAM Cl, PAM I>HI 6; meanwhile, HI 6 showed a strong direct physiological antagonistic.
出处
《军事医学科学院院刊》
CSCD
北大核心
1997年第3期205-207,共3页
Bulletin of the Academy of Military Medical Sciences
