摘要
在乌拉坦麻醉兔上分离坐骨神经－腓肠肌，正中神经－旋前圆肌标本，分别用单脉冲、５Ｈｚ、５０Ｈｚ和１００Ｈｚ持续２ｓ的串脉冲刺激，同时记录神经腓肠肌和旋前圆肌的诱发电位和收缩幅度的变化。用可逆性胆碱酯酶抑制剂——福定碱治疗实验性自身免疫性重症肌无力（ｅｘｐｅｒｉｍｅｎｔａｌａｕｔｏｉｍｍｕｎｅｍｙａｓｔｈｅｎｉａｇｒａｖｉｓ，ＥＡＭＧ）兔。
The experiments were performed in rabbits anaesthetized with urethane. Median nerve pronator teres and sciaticnerve gastrocnemius preparations were separated from fore legs and hind legs respectively. Action potential and contraction of pronator teres and gastrocnemius induced by various stimulus single. (5, 50, 100 Hz) were traced synchronously. The effects of reversible ChE inhibitor-fordine on action potential and contraction of pronator teres and gastrocnemius were observed in experimental myasthenia gravis rabbits.
出处
《军事医学科学院院刊》
CSCD
北大核心
1997年第3期211-213,共3页
Bulletin of the Academy of Military Medical Sciences
关键词
重症肌无力
诱发电位
肌收缩
电生理学
福定碱
myasthenia gravis
evoked potentials
muscular contraction
electrophysiology
action potentials
