慢性肾脏病患者生活质量的初步分析

Prelimimary study of quality of life among the patients with chronic kidney disease

目的应用改良的肾脏病生活质量量表1．3（KDQOL—SF^TM 1．3）对慢性肾脏病（CKD）患者的生活质量进行初步分析。方法采用问卷调查的方法收集44例门诊CKD患者的生活质量数据进行分析。结果18个维度中有11项α信度系数〉0．6，其中7项α信度系数超过了0．8。对反映简化36医疗结局研究量表（SF-36）的8个维度采用因子分析法，经最大方差旋转后产生2个主成分，共解释了64．66％的总方差。肾脏病相关生存质量（KDTA）总分与SF-36量表总分的相关系数为0．421。不同性别在“总体健康”一项中差异有统计学意义（P=0．026），肾功能正常与不全两组患者在“症状与不适”方面的差异具有统计学意义。“症状与不适”、“睡眠”、“社会的支持”、“疼痛”4项均与年龄呈负相关。结论本改良量表基本适合我国国情，但需进一步改良与完善。

Objective To study the quality of life among the patients with chronic kidney disease （CKD） through the modified KDQOL-SF^TM 1.3 short-form health survey. Method 44 patients with CKD were involved in this study. The data of KDQOL-SF^TM 1.3 short-forms were collected and analyzed. Results The modified KDOQI-SF^TM 1.3 showed internal consistency （every Cronbach α coefficients of 11 dimensions was greater than 0. 60）. Factor analysis resulted in two factors that were consistent with the theoretical hypothesis in some degree. They could be used to explain 64. 66% of the total variance. The correlation coefficient of the total score between the KDTA and the SF-36 was 0. 421. There was significant difference in ＂General health＂ between male and female （P〈0. 05）. There was also significant difference in ＂symptom/discomfort＂ between normal renal function griyo and renal failure group （P〈0. 05）. The scores of ＂symptom/discomfort＂, ＂sleep＂, ＂social support＂ and ＂pain＂ correlated with the age negatively （P〈0. 05）. Conclusions The modified KDQOL-SF^TM 1.3 is suitable to the condition of our country.