BPH患者尿道外括约肌运动单位电位正常值的检测

Clinical research of MUP of the external urethral sphincter of patients with BPH

目的：测定BPH患者尿道外括约肌运动单位电位（motor unit potential，MUP），统计出相应参数的正常值，为临床上发现“高危”BPH患者尿道外括约肌异常，降低“高危”BPH患者术后尿失禁发生率提供一定依据。方法：采用同心圆针电极经会阴穿刺至尿道外括约肌，用尿动力仪记录肌电信号，测定并记录BPH患者尿道外括约肌MUP。结果：本研究测定BPH患者80例，对每例患者收集符合标准的电位5～10个，记录每个电位的时限和波幅，经统计学分析得出，BPH患者尿道外括约肌MUP的参考值时限为3．46～11．26ms，平均7．36ms，波幅为55～607μV，平均237μV。结论：本研究得出BPH患者的MuP正常值可以用来评估预测相关“高危”BPH患者的尿道外括约肌可能存在的神经肌肉病变，对避免及分析术后尿失禁的原因具有一定的临床运用价值。

Objective： To test the MUP of external urethral sphincter in patients with BPH, and gain the parameter of the MUP, then calculate the reference value. So we can find the abnormality of external urethral sphincter in patients with BPH in time, which can reduce the incidence rate of urinary incontinence in patients with BPH. Methods：A concentric needle electrode was placed into the external urethral sphincter to record the sphincter EMG. The Duet multip urodynamics apparatus was used to measure the EMG of external urethral sphincter. Results： There are 80 patients with BPH,we record theduration and amplitude of each MUP,analyzed the data. The output is ： Duration is 3.46-11.26 ms,the mean is 7.36 ms,Amplitude is 55--607 μV, the mean is 237 μV. Conclusions：We find that the duration is more stable , which is the important index we observe often. When we compare some special patients＇ results to the reference value, we may find the potential neuromuscular pathological changes, then offer the correct and valid diagnosis and treatment.