ALQ与大剂量甲基强的松龙治疗脊髓损伤的对比实验

The Comparative Study of Treatment in Experimental Spinal Cord Injury by Autohemotherapy of Light Quanta with High-dose Methylprednisolone Sodium Succinate

目的：论证自血光量子疗法（ALQ）治疗脊髓损伤的可靠性。方法：56只家兔用改良Allen氏法造成不完全性脊髓损伤，通过运动功能、脊髓诱发电位、病理和丙二醛检查，将ALQ与大剂量甲基强的松龙（MP）进行实验对比研究。结果：运动功能、脊髓诱发电位及病理改变二组疗效相似；脊髓丙二醛含量ALQ治疗组较大剂量MP治疗组显著降低。结论：大剂量MP需要伤后立即治疗，而ALQ可以在伤后2天开始进行．疗效满意，因此更具有临床实验性。

This study's aim is to demonstrate further the reliability of treatment in spinal cord injury by autohemotherapy of light quanta (ALQ). After fifty- six rabbits with spinal cord injury by improved Allen's methord, ALQ was studied by comparison with high - dose methylprednisolone sodium succinate (MP) through exams of movement function,spinal cord evoked potentials,pathologic histology and malondiadehyde. The experiment demonstrated that curative effect on movement function,spinal cord evoked potentials and pathologic histology were similar among two therapeutic groups,the content of spinal cord malondiadehyde of the therapeutic group of ALQ reduced more significantly than the group of high -dose MP. The experiment advanced that highdose MP needs to be carried out immediately after injury,but ALQ may be done two days after injury and its curative effect is satisfied,so it has more clinical applicability.