经阴道彩色多普勒超声对体外受精-胚胎移植卵巢反应性的评估价值

Evaluation of ovarian response during in-vitro fertilization using transvaginal color Doppler ultrasonography

目的探讨卵巢体积、窦状卵泡数、卵巢基质动脉血流对体外受精与胚胎移植（IVF-ET）中卵巢反应性的预测价值。方法应用经阴道彩色多普勒超声对131例接受IVF-ET的不孕症患者于控制性超排卵（COH）周期启动日及人绒毛膜促性腺激素（HCG）注射日进行卵巢体积、窦状卵泡数和卵巢基质动脉搏动指数、阻力指数检测。结果131例患者中临床妊娠49例，妊娠率为37．40％。周期启动日及HCG注射日，妊娠组总卵巢体积、窦状卵泡数均大于未妊娠组（P〈0．05），卵巢基质动脉搏动指数、阻力指数均小于未妊娠组（P〈0．05）。结论经阴道彩色多普勒超声可通过检测卵巢体积、窦状卵泡数和卵巢基质动脉搏动指数、阻力指数，无创性预测卵巢反应性，评估IVF-ET妊娠结局。

Objective To investigate the role of ovarian volume, antral follicle count and ovarian stromal blood flow in assessing ovarian response in an in vitro fertilization （IVF） program. Methods One hundred and thirty one patients undergoing IVF cycles were recruited. Transvaginal color Doppler was performed on the priming day and human chorionic gonadotropin （hCG） injection day to determine ovarian volume, antral follicle count, pulsatility index（PI） and resistance index（RI） of ovarian stromal artery. Results The pregnancy rate was 37.400% （49/131）. Total ovarian volume, antral follicle count on the priming day and HCG injection day were significantly higher in the pregnant group than those in the non-pregnant group （ P 〈0.05）. Ovarian stromal artery PI, RI on the priming day and HCG injection day were significantly lower in the pregnant group than those in the non-pregnant group （ P 〈0.05）. Conclusions Ovarian volume,antral follicle count, ovarian stromal artery PI, RI measured by Doppler are good predictors of ovarian response in IVF-ET.