3,5-二卤代-4-羟基苯甲腈的合成

Study on Synthesis of 3,5 Dihalogeno 4 hydroxybenzonitrile

对羟基苯甲酸在溶剂中与尿素反应生成对羟基苯甲腈，产物分别与溴素和氯酸钠、碘和氯气反应制得相应的３，５－二卤代－４－羟基苯甲腈。

p Hydroxybenzonitrile was obtained by the reaction of p hydroxybenzoic acid with urea in solvent, then reacted with bromine and sodium chlorate, iodine and chlorine respectively to form the corresponding 3,5 dibromo 4 hydroxybenzonitrile and 3,5 diiodo 4 hydroxybenzonitrile.