生物降解聚合物膜的制备及防肌腱粘连作用

Preparation of Biodegradable Polymer Films for Prevention of Tendon Adhesion

生物降解聚合物膜的制备及防肌腱粘连作用甘志华景遐斌＊（中国科学院长春应用化学研究所高分子物理联合开放研究实验室长春１３００２２）张仲文徐莘香（白求恩医科大学第一临床医院长春）关键词肌腱粘连，生物降解，聚合物膜１９９６－０７－２１收稿，１９９６－０９－...

ε Caprolactone( ε CL)/ d,l lactide(DLLA) copolymer films with thickness of 40 μm were prepared by solution casting and implanted into rabbit body to cover the ruptured achilles tendons for preventing tendon adhesion with surrounding tissues. The biodegradation of ε CL homopolymer film and ε CL/DLLA copolymer film in rabbit body were also studied. The ε CL/DLLA copolymer film could decrease postoperative adhesion of the tendon, and it degraded entirely within 24 weeks.